Evaluation of the Effect of Progesterone and Placebo in Parturient of Symptomatic Placenta Previa: A Prospective Randomized Control Study

نویسندگان

  • Poonam Singh
  • Sanjeev Kumar Jain
چکیده

Background: Antepartum hemorrhage and placenta previa effects majority of pregnant women endangering their life both maternal and fetal. Symptomatic placenta previa are being treated with tocolytic agents. Progesterone is the most common used drug for the preservation of pregnancy and aids in the extension of pregnancy. Materials and Methods: A 80 patients were randomly assigned to two groups using computer-generated randomization. Group A (40 patients) received a placebo twice a week and Group P (40 patients) received injection 17α-hydroxyprogesterone caproate (500 mg, IM). Various complications related to mother and fetus were compared in both the groups. Result: Signifi cant difference was seen in the elongation of pregnancy, gestational age at the time of delivery and birth weight of the fetus. Conclusion: In the present study, 17α OH progesterone use in the hopeful management of symptomatic placenta previa inclines to be valuable than placebo, thus reducing the maternal and fetal complications.

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تاریخ انتشار 2015